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AbSynth - a century-spanning, machine-readable data set of 3077 total syntheses - is now available

 
 

This work was completed by undergraduate students (from the 1904 Undergraduate Chemistry Club at the Jagiellonian University) working under the guidance of researchers in various institutions internationally (Allchemy, JU, IOC PAS, IBS), including several Ph.D students and undergraduates in our lab. Congratulations to Yasemin, Louis, Konrad, Ahmad and Maxence and the rest of the team on remarkable contribution to advancement of chemical AI !  

 

Read the article here. 

 

The collection of 3,077 total syntheses comprising ~ 60,000 individual reaction steps  can be viewed in the  AbSynth portal  and is made freely available to academic users in digital form from  https://allchemy.net/#absynth.

 

AbSynth: A Century of Total Syntheses as a Machine-Readable Resource for Analyzing Strategic Logic in Organic Chemistry

Maciej Czuba, Konrad Barnowski, Karol Molga, Zofia Plawecka, Agnieszka Wolos, Szymon Stodolkiewicz, Sebastian Bas, Wojciech Petrykowski, Wiktor Beker, Evan Saillard, Konrad Legowski, Rafal Roszak, Pawel Kowalczyk, Barbara Mikulak-Klucznik, Piotr Janasz, Emilia Mielke, Patrycja Pietruszewska, Maja Lazuchiewicz, Sylwia Wojcik, Jakub Zabielski, Dariusz Nostkiewicz, Gabriela Smaga, Ahmad Makkawi, Louis PJ-L Gadina, Jakub Skoczek, Tomasz Klucznik, Maxence Deschamps, Anna Zadlo-Dobrowolska, Michal Michalak, Sara Szymkuc, Daniel T Gryko, Yasemin Bilgi-Gadina & Bartosz A. Grzybowski. 

J. Am. Chem. Soc. 148, 38740-38753 (2026).

 



 

Posted on October 5, 2026

 

  Before

Daniel's paper on hyperspace exploration of Biginelli reaction was published in Nature Synthesis 

 

 

 


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